Pre-B ALL is a subtype of acute lymphoblastic leukemia (ALL), which is a cancer of the white blood cells that affects mostly children and young adults. Pre-B ALL specifically affects the B lymphocytes, which are a type of white blood cells that normally produce antibodies to fight off infections. In pre-B ALL, abnormal B cells called lymphoblasts rapidly increase in number, crowding out healthy blood cells and impairing the immune system's ability to fight infections.
Symptoms of pre-B ALL can include fatigue, weakness, fever, frequent infections, easy bruising or bleeding, swollen lymph nodes, and bone or joint pain. It is often diagnosed through blood tests, bone marrow biopsy, and genetic testing.
Treatment for pre-B ALL typically involves chemotherapy, which uses drugs to kill cancer cells, followed by a stem cell transplant to replace damaged bone marrow with healthy cells. The prognosis for pre-B ALL varies depending on the individual case, but with early detection and aggressive treatment, many patients have a good chance of achieving remission and living a normal life.
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